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ey0017.5-5 | Advances in Clinical Practice | ESPEYB17

5.5. Six-year follow-up of a trial of antenatal vitamin D for asthma reduction

AA Litonjua , VJ Carey , N Laranjo , BJ Stubbs , H Mirzakhani , GT O’Connor , M Sandel , A Beigelman , LB Bacharier , RS Zeiger , M Schatz , BW Hollis , ST Weiss

To read the full abstract: N Engl J Med. 2020;382(6):525533.In brief: High dose vitamin D supplementation of 4400 IU compared with 400 IU during the prenatal period alone to mothers of offspring at risk for asthma did not influence the incidence of asthma and recurrent wheeze in children aged 6-years.Commentary: Vitamin D deficiency has been im...

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ey0019.15-10 | Assorted Conditions | ESPEYB19

15.10. Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma

P Kachroo , ID Stewart , RS Kelly , M Stav , K Mendez , A Dahlin , DI Soeteman , SH Chu , M Huang , M Cote , HM Knilhtila , K Lee-Sarwar , M McGeachie , A Wang , AC Wu , Y Virkud , P Zhang , NJ Wareham , EW Karlson , CE Wheelock , C Clish , ST Weiss , C Langenberg , JA Lasky-Su

Nat Med. 2022;28(4):814-22. doi: 10.1038/s41591-022-01714-5.PubMed ID: 35314841Brief summary: This study performed large-scale metabolomic profiling across 14 000 adults from 4 cohorts and identified 17 steroid metabolites whose levels were reduced in individuals with prevalent asthma. The largest reductions were associated with inhaled corticosteroid (ICS) treatment, and these were valida...

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ESPE Yearbook of Paediatric Endocrinology

5.5. Six-year follow-up of a trial of antenatal vitamin D for asthma reduction

15.10. Metabolomic profiling reveals extensive adrenal suppression due to inhaled corticosteroid therapy in asthma

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